Among the immune-related traits, the KEGG pathway “JAK-STAT signaling pathway” was ranked the most significant in CD (pcombined = 2.76 × 10− 7), RA (pcombined = 1.62 × 10− 5), and UC (pcombined = 2.48 × 10− 9). The gene discussed is SOAT1; the disease is rheumatoid arthritis.