Therefore, some studies have focused on chemical substances that could act as potential FMO3 inhibitors to prevent or treat atherosclerosis.97, 98, 99 Gao et al found that the binding of methimazole and indole could provide evidence for the development of human FMO3 inhibitors.97 Indole‐3‐carbinol (I3C) and its acid condensation products, I33’ and LT, were reportedly responsible for the inhibitory activity of human FMO3.98 Therapeutically, the aim was to develop targeted drugs for the intervention of certain CVDs. Here, FMO3 is linked to atherosclerosis.