Mutations in PTEN, ARID1A, PIK3CA, PIK3R1, beta-catenin, CTCF, and KRAS, are often found in endometrial tumors with endometrioid histology [8, 138], with a mutation in at least one of these genes found in 94% of tumors. This evidence concerns the gene CTNNB1 and endometrium neoplasm.