In addition, the area under receiver operator characteristic curve (95% confidence interval) of TG/HDL-C for NAFLD was 0.85 (0.84–0.86) in women and 0.79 (0.78–0.80) in men, significantly higher than that of TG, TC, LDL-C, HDL-C, ALT and AST (P <  0.05). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.