To date, some natural and synthetic agents with both antibacterial and LPS-binding and neutralizing activity, mostly from the group of cationic antimicrobial peptides (AMPs), were presented as potential candidates for treatment of microbial-related diseases, including sepsis, LPS-induced inflammation during cystic fibrosis lung disease and skin infections [6, 41, 42]. The gene discussed is ADSL; the disease is Sepsis.