FOXO1 and type 2 diabetes mellitus: T2D leads to significant changes in the expression of transcription factors forkhead box protein 1 (FOXO1, 1.7 ± 0.3 ↑, P < 0.05), and peroxisome proliferator‐activated receptor‐alpha (PPAR‐α, 2.1 ± 0.3 ↑, P < 0.01) (Figure 3E), while PPAR‐γ expression did not differ between T2D and ND.