CD47 and diffuse large B-cell lymphoma: Therefore, the impact of targeting of CD47 using F(ab′)2 fragments was also assessed for M0 and M2 macrophages, with increased phagocytosis of DLBCL cells upon treatment being detected for macrophages differentiated into M1 (LPS/IFN-y), M2 (IL-10), and M0 (M-CSF/GM-CSF) macrophages (Fig. 2f, g).