Bioinformatic analysis of WES and CGH-array data selected 15 common for psychosis phenotype damaging variants and 6 of them were rare mutations, including paternal 3p26.3-loss and 5 additional missense mutations located in ACSF2, MPRIP, PHC1, PER3, and RERE genes. Here, ACSF2 is linked to psychotic disorder.