CNR2 and glioblastoma: Furthermore, we aimed at characterizing the antiproliferative/proapoptotic properties of the CB1 agonist ACEA, CB1 antagonist/inverse agonist AM281, CB2 agonist JWH133, and CB2 antagonist/inverse agonist AM630 in the three glioblastoma cell lines U-138 MG, U-87 MG, and LN229.