GBA1 and Cognitive impairment: Carriers of glucosylceramidase β (GBA [OMIM *606463]) gene mutations, for instance, have a greater probability of developing cognitive impairment, postural instability, and falls.1 Carriers of PRKN (OMIM *602544), PINK1 (OMIM *608309), and DJ-1 (OMIM *602533) gene mutations, on the contrary, exhibit milder progression of motor and nonmotor features.2