The C allele is likely to inhibit the expression of BRCA2 by interfering with the processing of this pre‐miRNA and increasing the expression of target genes such as BRCA2. Because one of the early onset genes in breast cancer is the BRCA2, the presence of any of C and T alleles can have a significant effect on the incidence of the disease. This evidence concerns the gene BRCA2 and breast carcinoma.