The endogenous AD‐MSCs from AIMP3 TGs were less responsive to the autophagy‐inducing rapamycin; however, while autophagy in AD‐MSCs from WT mice was increased by approximately twofold by rapamycin, the cells from AIMP3 TGs did not exhibit rapamycin‐mediated autophagy induction (Figure 5b). This evidence concerns the gene EEF1E1 and Alzheimer disease.