Although we cannot explain why there was a different outcome of myeloid cell-specific Lpcat3 deficiency and hematopoietic cell-specific Lpcat3 deficiency, in terms of mouse atherosclerosis, we speculate that, owning to their hematopoietic origin, Lpcat3 KO fetal liver also harbored Lpcat3 KO B-cells, T-cells, mast cells, and granulocytes in the Lpcat3 KO chimeric mice (Lpcat3 KO fetal liver cells → Ldlr KO) (30). This evidence concerns the gene LPCAT3 and atherosclerosis.