CD36 and Hyperinsulinemia: The Rhodiola crenulata extract significantly suppressed fructose-induced hyperinsulinemia and increased the homeostasis model assessment of insulin resistance (HOMAR-IR) index and the adipose tissue insulin resistance index in male Sprague Dawley rats, indicating that the amelioration of insulin resistance by R. crenulata extract is attributable to its modulation of the sarcolemmal and intracellular redistribution of CD36 [69].