HLA-E and chronic myelogenous leukemia, BCR-ABL1 positive: Indeed, the NK cells isolated from CML patients on dasatinib generally exhibited significantly higher cytotoxicity against HLA-E-expressing K562 cells (K562-e cells) at an E:T ratio of 12:1, compared with the cytotoxicity of the NK cells isolated from patients on imatinib or on nilotinib.