GHRL and hyperlipidemia: pylori eradication therapy often causes individuals with nomal renal function to develop hyperlipidemia and hyperproteinaemia, along with an increase of body weight and body mass index (BMI).(19) This phenomenon is considered to be due to increases in plasma ghrelin level followed by increased appetite and food intake after H. pylori eradication therapy.(20,21) In general, ghrelin is down-regulated by H. pylori infection and up-regulated by H. pylori eradication therapy.