Secretogranin-1 has been identified in biopsy specimens of medullary thyroid carcinoma patients by LC-MS/MS.(27) Kroksveen et al.(28) reported that secretogranin-1 is increased in the cerebrospinal fluid of early multiple sclerosis patients, and may be used as a biomarker of this disease. Here, CHGB is linked to medullary thyroid gland carcinoma.