The CCNH-C5orf30 transcript was also detected in 7 different types of human cancers with the following relatively high frequencies: 85% (51/60) in breast cancer, 43% (26/60) in colon cancer, 50.8% (31/61) in ovarian cancer, 67.6% (23/34) in esophageal adenocarcinoma, 41.8% (59/141) in non-small cell lung cancer, 37% (26/70) in liver cancer and 53% (80/150) in glioblastoma multiforme. Here, MACIR is linked to esophageal adenocarcinoma.