To investigate whether fusion genes play a role in other human malignancies, we analyzed six fusion genes, including TRMT11-GRIK2, MTOR-TP53BP1, CCNH-C5orf30, KDM4-AC011523.2, TMEM135-CCDC67, and LRRC59-FLJ60017, in primary cancer samples from 7 different types of human malignancies and 20 cancer cell lines originating from 6 human cancers. This evidence concerns the gene TP53BP1 and cancer.