HAS1 and Waldenstrom macroglobulinemia: Besides, some genes are involved in osteoblastogenesis (SEMA3A, BICC1, CHRLD1, and ZNF521) and HAS1 is involved in Waldenstrom’s macroglobulinemia (Table 3), a post-follicular B-cell lymphoproliferative disorder also associated with M-protein production (IgM).