We only identified one published association of SNPs within ABHD8 with a disease trait (breast cancer) in the literature [64], although it is notable that this gene lies in head-to-head orientation with mitochondrial ribosomal protein L34, MRPL34. Another mitochondrial ribosomal protein, MRPL37, has previously been found to associate with mtDNA CN, which [20] raises the possibility that the BABAM1-ANKLE1-ABHD8-MRPL34 locus might be a true signal, despite the lack of evidence of effect in our main analyses. The gene discussed is ANKLE1; the disease is breast carcinoma.