Gensini scoring can be used to measure the severity of coronary artery lesions by adopting the method of quantitative coronary angiography in which different weights are adapted for different degrees of severity, and the result of the scoring is mainly correlated to the degree of coronary artery stenosis and scope of blood supply [24], namely, the lower the relative expression level of the PRMT5 gene, the higher the Gensini score, and the more severe the coronary artery lesion. The gene discussed is PRMT5; the disease is coronary stenosis.