Of note, splenocytes from mice immunized with B16 or LLC tumor lysate-pulsed BMDCs could also be activated under placental gp96 stimulation (both P<0.05 compared to liver gp96-pulsed BMDC immunization), suggesting antigen overlap between placental gp96-chaperoned peptides and tumor antigens from melanoma or lung carcinoma. The gene discussed is HSP90B1; the disease is neoplasm.