For example, following natural infection with V. cholerae, MBC responses remain detectable longer than other immunologic responses after a V. cholerae infection[21]; and the presence of detectable circulating IgA or IgG OSP MBCs are predictive of protection against V. cholerae following infection[5] or vaccination[22], even in exposed individuals without persistently elevated levels of circulating vibriocidal antibodies[5]. Here, CD79A is linked to infection.