ANGPT2 and angina pectoris: It is worthy to note that in some patients with recurrent severe angina, it is not observed of any restenosis artery through the repeat coronary angiography, which is probably due to endothelium-dependent coronary microvascular dysfunction.[32] According to this study, patients with post-PCI Ang-2 levels higher than the median value had a significant increase in the risk of cardiovascular events during the first 1.5 years after PCI compared with patients whose post-PCI Ang-2 levels were lower than the median value.