1990; Frostegård et al. 1992; Rosklint et al. 2002). Soluble forms of the adhesion molecules such as VCAM-1 and ICAM-1 can be detected in plasma and are a good indicator of their availability on the cell membrane (Raffray et al. 2017). Also, in preclinical practice and experimental studies, one surrogate marker to detect atherosclerosis is the measurement of blood vessel IMT (Stein et al. 2008). In the general population, the Offspring Cohort of the Framingham Heart Study (OCFHS) demonstrated a direct association between inflammatory markers and IMT (Stein et al. 2008). The gene discussed is VCAM1; the disease is atherosclerosis.