PGR and ovarian carcinoma: Indeed, progesterone and progestin were shown to play a protective role against ovarian carcinogenesis (Edmondson & Monaghan, 2001), and PR expression was a favorable prognostic marker associated with longer progression-free survival in ovarian cancer patients (Tangjitgamol et al., 2009; Van Kruchten et al., 2015; Wong et al., 2007).