HDAC9 and medullary thyroid gland carcinoma: Here we use this animal model to characterize and compare the anti-cancer effect and modes of action of an established MTC drug, i.e., Vandetanib, and that of two experimental TKI-based MTC treatments, Nintedanib alone and in combination with the HDAC inhibitor, Romidepsin, which has previously been co-administrated with TKIs.