SPO11 and cancer: A number of meiosis-specific CT genes including, but not limited to SPO11 [12], STRA8 [17], DMC1 [18], REC8, STAG3 [18], SGO2 [12], SYCP1/2/3 [18] and HORMAD1 [12] have been shown to be expressed in various solid and hematological cancers as well as in different cancer cell lines.