As one of the possible mechanisms of action in helping to control GBM, we tested the effect of progesterone treatment on the expression of the key regulators of glycolytic metabolism Glut1, GAPDH, FoxO1 and phospho-FoxO1, in U87MG-luc, U87dEGFR and U118MG cell lines. The gene discussed is SLC2A1; the disease is glioblastoma.