As one of the possible mechanisms of action in helping to control GBM, we tested the effect of progesterone treatment on the expression of the key regulators of glycolytic metabolism Glut1, GAPDH, FoxO1 and phospho-FoxO1, in U87MG-luc, U87dEGFR and U118MG cell lines. Here, GAPDH is linked to glioblastoma.