HSP also appears to be associated with cancer-relevant factors, such as the hypoxia-inducible factor HIF1A, the prominent tumor suppressor TP53, CDK1, SRC, MYC, NOS3, VEGFA, EGFR, ERBB2, MAPK1, AKT1/2, and RPS6KB1. This evidence concerns the gene HIF1A and neoplasm.