3.2. Effects of RMD on the Activities of Acetyl-CoA Carboxylase (ACC), Fatty Acid Synthase (FAS), and HMG-CoA Reductase (HMGCR) and Lipid Metabolism-Related Signaling Molecules in the Liver of HF-Diet-Fed Rats. The gene discussed is HMGCR; the disease is hydrops fetalis.