GCC2 and lung carcinoma: However, in three patients with lung cancer, the GCC2 gene was shown to fuse with anaplastic lymphoma kinase (ALK; MIM #105590), which has a critical role in the pathogenesis of non‐small cell lung cancer, and targeting it with crizotinib was shown to be active against cancer (Jiang et al., 2018; Noh et al., 2017; Vendrell et al., 2017).