JAK2 and cancer: The Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway is considered to be one of the most significant and active signalling pathways in cells that transduce signals downstream to cytokines, growth factors and hormones.3 It has been verified that inhibition of JAK2/STAT3 pathway could suppress migratory and invasive potential in some cancers.