LEP and colorectal carcinoma: Another study also identified similar findings regarding CRC in mixed populations.30 A previous meta‐analysis indicated that a tendency to decrease risk was noted between LEP G19A polymorphism and cancer.15 However, for Asian population, only two case‐control studies with small sample sizes were included in this pooled analysis.22, 23 The association of LEP G19A polymorphism with cancer risk in Asians was unclear.