In the past few decades, some case‐control studies have been designed to explore the potential relationship between G19A polymorphism in the LEP gene and the risk of cancer.16, 17, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31 Skibola et al24 found that LEP G19A polymorphism decreased the risk of NHL in Caucasians. Here, LEP is linked to cancer.