It is found that the LEP rs2167270 G > A (G19A) locus is correlated with LEP levels and may also give a fascinating insight into the potential correlations with the development of cancer.13, 14 In a previous pooled study, it was found that individuals carrying a LEP 19A allele might have a lower tendency for cancer risk.15 However, most of the eligible studies focused on Caucasians. The gene discussed is LEP; the disease is cancer.