This observation of synergism was made even more interesting when infection combined with a novel hydrazone derivative [N'-(2-chlorobenzylidene)-4-(2-(dimethylalamino)ethoxy) benzohydrazide)] H2, the cytotoxic effect against MDA-MB-231 increased to a significant level as compared to only rMV or rMV-BNiP3 infected cells. This evidence concerns the gene BNIP3 and infection.