SIGLEC16 and infection: While activating receptors such as Siglec‐14 and Siglec‐16 may contribute to a pro‐inflammatory response following infection facilitate clearance of infection, N. gonorrhoeae have developed numerous mechanisms to survive within neutrophils that are abundant at the site of infection upon pro‐inflammatory stimuli, which could form a “safe haven” for bacteria (Criss & Seifert, 2012).