Two such documented examples include human‐specific pathogens group B streptococcus which engages Siglec‐9 on neutrophils and Siglec‐5 on the amniotic epithelium (Ali et al., 2014; Carlin et al., 2007) and E. coli K‐1 which engages Siglec‐11 on brain microglia, likely suppressing their microbicidal activity during the process of causing meningitis (Schwarz et al., 2017). The gene discussed is SIGLEC11; the disease is meningitis.