The N. gonorrhoeae PorB.1A strain 15253, which was isolated from a disseminated infection, bound significantly better to human Siglec‐3 (p = 0.037), Siglec‐5 (p = 0.011), Siglec‐9 (p = 0.009), and Siglec‐14 (p = 0.002) than to its chimpanzee homolog (Figure 2b). Here, SIGLEC5 is linked to infection.