Meanwhile, current evidence has also shown a ethnicity-specific and subtype-specific correlation between PIP4K2A SNPs and ALL susceptibility (Migliorini et al., 2013; Walsh et al., 2013; Xu et al., 2013), which is similar as ARID5B SNPs (Xu et al., 2012, 2013). The gene discussed is ARID5B; the disease is acute lymphoblastic leukemia.