Similarly, diets rich in saturated milk-derived fat favor the growth of the pathobiont Bilophila wadsworthia (BW) in the colon of IL-10−/− mice, increasing the incidence of spontaneous colitis (69), and SPF mice colonized with BW present higher expression of IL-6 and Serum Amyloid A (SAA), exhibiting systemic inflammation (84). The gene discussed is IL10; the disease is colitis.