HTR1A and alcohol dependence: Neuropharmacological studies have shown that multiple 5-HT receptor subtypes, such as 5-HT1A/1BR, 5-HT2A/2CR, 5-HT3R, and 5-HT7R, are involved in the development of alcohol dependence (Sari et al., 2011; Yoshimoto et al., 2012; Hauser et al., 2015).