CRABP2 and metastatic malignant neoplasm in the lymph nodes: Using blood buffy coat samples from lung cancer patients (n = 48), our results showed significantly higher CRABP2 levels in patients with advanced lymph node metastasis (N2-3) than those having none or early lymph node metastasis (N0-1) (p = 0.0089, Fig. 2a).