At day 180, proinflammatory cytokine production were even higher than in healthy controls, both in response to mycobacterial stimuli as shown before20, as well as to unrelated stimuli C. albicans and S. pneumoniae. Our findings show similarities to HIV-associated cryptococcal meningitis with proportionally overrepresented CD56bright NK cells and CD14++CD16+ and CD14+CD16++ monocytes in CSF compared to blood21 and a subgroup of patients with low HLA-DR on monocytes and low ex-vivo TNF-α22. This evidence concerns the gene CD14 and Cryptococcal meningitis.