Similar, we transfected BECN1-WT (wide type) and BECN1ΔBH3 into HCC cells and witnessed BECN1ΔBH3 failed to co-immunoprecipitate with BCL2L10, which confirmed BH3 domain on BECN1 was essential to bind to BCL2L10 (Supplementary Figure 1E). This evidence concerns the gene BECN1 and hepatocellular carcinoma.