NFKB1 and infection: Notably, in the presence of K288R STING, which only activates NF‐κB, but not IRF, signaling viral transcript levels upon infection with MCMV m152stop were significantly higher compared to iMEFgt/gt, in which the type I IFN response is completely abrogated, and in iMEFgt/gt stably expressing WT STING, which can mount an IRF response unaffected by m152 (Fig 8E).