Although the number of CD8+ T cells in the draining lymph node of αCD4- or mH/αCD4-treated mice were equivalent (Additional file 1: Figure S4B), the density of CD8+ T cells in the tumor was higher in the mH/αCD4-treated mice than in the αCD4-treated mice (p = 0.03) (Fig. 2b, c). Here, CD8A is linked to neoplasm.