TGFB1 and cancer: The differential gene KEGG pathway enrichment analysis showed that the up-regulated pathways were the NF-κB signaling, HIF-1 signaling, apoptosis, cancer, and autophagy pathways, and the downregulated pathways were adhesion, citric acid cycle, conduction pathway, MAPK signaling pathway, TGF-β signaling pathway, P13K-Akt signaling pathway, and cell cycle.