In the HFD/Fucoidan-ischemia group, SOD1 and SOD2 immunoreactivity in CA1 pyramidal cells was decreased with time after tGCI, but each immunoreactivity was higher than that in the HFD-ischemia group (Figure 8Aj–Al, C and Figure 10Aj–Al, C). Here, SOD2 is linked to ischemia.