This translated into aberrant CD25, CD30, and CD123 expression levels on BMMC from SM patients (vs. normal/reactive BMMC), both in terms of SI (p = 0.001) (Figure 1B,C,E) and mean fluorescence intensity (MFI) values (p = 0.001) (Table 2). Here, TNFRSF8 is linked to systemic mastocytosis.