PECAM1 and ovarian adenocarcinoma: This finding is consistent with T1 increases that have been observed after vascular normalization induced by anti‐angiogenic drugs.7, 31, 35 For example, T1 increased when microvascular density and proliferation (determined from CD31 and Ki67 staining, respectively) decreased in a mouse model of ovarian adenocarcinoma receiving anti‐angiogenic therapy.7