H19 is transcribed by RNA polymerase II and dysregulation of H19 is associated with BRC, CRC, GC, Glioblastoma, HCC, HNC, LC and NSCLC (Hu et al., 2016; Matouk et al., 2016; Chen et al., 2017b; Luo et al., 2017). The gene discussed is H19; the disease is laryngotracheoesophageal cleft.