CHD8 and schizophrenia: The gene encoding chromodomain helicase DNA binding protein 8 (CHD8) has one of the highest observed mutation rates in sporadic ASD (O’Roak et al., 2012a; Krumm et al., 2014; Barnard et al., 2015), and mutations to CHD8 have also been identified in cases from schizophrenia and intellectual disability cohorts (McCarthy et al., 2014; Tatton-Brown et al., 2017).